VesselMax
$45.90
Clinical Applications
- Promotes Healthy Microcirculation
- Helps Support Blood Vessel and Cardiovascular Health
- Maintains Optimal Vasomotor and Vascular Tone
The muscles of blood vessels need to receive constant stimulation to maintain a resting level of contraction. This phenomenon is known as vasomotor tone. Vasoconstriction, whether due to an increase in venous wall stress or biomechanical stretch, is sufficient to cause an increase in vasomotor tone. Narrowing blood vessels leads to a reduction in blood supply and consequently a reduction in oxygen supply to various organs and tissues.
VesselMax is a powerful blend of botanical extracts shown to promote healthy microcirculation and support vascular strength and tone. The four ingredients in VesselMax work synergistically to support all layers of blood vessel structure.
Suggested Use:
3 capsules per day or as recommended by your health care professional.
Overview
The muscles of blood vessels need to receive constant stimulation to maintain a resting level of contraction. This phenomenon is known as vasomotor tone. Vasomotor tone is, in turn, the result of a complex set of interactions that control both the relaxation and contraction of blood vessels.1 This tone maintains the diameter of blood vessels and plays a vital role in maintaining healthy blood pressure levels within the normal range. Vasomotor tone is also controlled by the sympathetic nervous system, which releases norepinephrine to stimulate the appropriate response to various hormones and physiologic situations.
Vasoconstriction, whether due to an increase in venous wall stress or biomechanical stretch, is sufficient to cause an increase in vasomotor tone. Narrowing blood vessels leads to a reduction in blood supply and consequently a reduction in oxygen supply to various organs, making this a critical factor for maintaining optimal energy and health. Furthermore, such changes in vasomotor tone impact cardiac output and may lead to oxygenation and microcirculatory challenges.
Recent research proves flavonoids are natural substances that have special circulatory system benefits and support optimal circulatory function. They also play a key role in microcirculation
and optimal blood flow. Particularly, troxerutin, diosmin and horse chestnut extract appear to protect blood vessels from oxidative stress and are specifically well-suited to support those with circulatory and venous tone challenges.2
Diosmin
Diosmin is derived from the bioflavonoid hesperidin found in citrus rinds. The diosmin used in VesselMax is refined through micronization, which results in minute particles that are significantly smaller in size than standard diosmin. This allows for rapid, efficient delivery to the bloodstream and the inner lining of veins. Micronized purified flavonoid fraction (MPFF) supports vascular health by prolonging the impact norepinephrine has on the vessel wall, which promotes venous tone. In addition to promoting venous tone, research shows diosmin promotes circulatory health by helping to improve lymphatic drainage and protecting microcirculation.3 It has also been shown to maintain normal inflammatory balance and decrease capillary permeability.3
Troxerutin
Troxerutin is a naturally occurring flavonoid that is isolated from tea, coffee and vegetables. It has a variety of activities, including strong antioxidant capacity and the ability to maintain normal inflammatory balance.4 Specifically, troxerutin is able to promote healthy microcirculation and protect endothelial cells from oxidative stress. In a 2015 study, 134 patients received a mixture of diosmin, troxerutin and hesperidin for circulatory challenges, and this mixture was found to be a safe and effective for maintaining healthy venous sufficiency.5
Gotu Kola
Gotu kola (Centella asiatica) is a perennial plant found throughout India in moist places up to an altitude of 1800 m, and the whole plant is used for many health benefits.6 The primary active constituents of gotu kola are saponins, also called triterpenoids, which include asiaticosides.7 These triterpene saponins are mainly responsible for this plant’s vascular benefits and ability to help with normal tissue repair.8 Gotu kola stimulates collagen synthesis and helps improve the tone and elasticity of vascular walls. It has also been shown to improve microcirculation and promote healthy capillary permeability. In addition, gotu kola supports functional parameters of healthy venous structure and hemodynamics.9,10
Horse Chestnut Extract
Horse chestnut extract (Aesculus hippocastanum) is native to Southeastern Europe. Its seed extracts and their concentrates contain phytocompounds, including flavonoids, polyphenols, triterpenoid saponin glycosides (aescin), epicatechin, tannins, kaempferol, esculin, and fraxin, with aescin as the chief bioactive compound.11
Aescin gives this herb its ability to promote healthy venous tone normal lymph drainage and favorable blood flow dynamics.11 It is also beneficial in improving microcirculation, which is the venous network responsible for the circulation of blood from the heart to the capillaries and back to the heart. Maintaining the structural integrity of capillaries is imperative for proper functioning of the venous system overall. Research indicates Ruscus extract and horse chestnut seed demonstrate the ability to maintain healthy venous sufficiency.12
Directions
3 capsules per day or as recommended by your health care professional.
Does Not Contain
Gluten, yeast, artificial colors or flavors.
References
- Fields CE, Makhoul RG. Vasomotor tone and the role of nitric oxide. Semin Vasc Surg. 1998;11(3):181-192.
- Casili G, Lanza M, Campolo M, et al. Therapeutic potential of flavonoids in the treatment of chronic venous insufficiency. Vascul Pharmacol. 2021;137:106825. doi:10.1016/j.vph.2020.106825
- Ramelet AA. Clinical benefits of Daflon 500 mg in the most severe stages of chronic venous insufficiency. Angiology. 2001;52 Suppl 1:S49-S56. doi:10.1177/0003319701052001S07
- Ahmadi Z, Mohammadinejad R, Roomiani S, Afshar EG, Ashrafizadeh M. Biological and Therapeutic Effects of Troxerutin: Molecular Signaling Pathways Come into View. J Pharmacopuncture. 2021;24(1):1-13. doi:10.3831/KPI.2021.24.1.1
- Giannini I, Amato A, Basso L, et al. Flavonoids mixture (diosmin, troxerutin, hesperidin) in the treatment of acute hemorrhoidal disease: a prospective, randomized, triple-blind, controlled trial [published correction appears in Tech Coloproctol. 2015 Oct;19(10):665-6]. Tech Coloproctol. 2015;19(6):339-345. doi:10.1007/s10151-015-1302-9
- Diwan PV, Karwande I, Singh AK. Anti anxiety profile of manduk parni Centella asiatica in animals. Fitoterapia. 1991;62:255-7.
- Singh B, Rastogi RP. A reinvestigation of the triterpenes of Centella asiatica. Phytochem. 1969;8:917–21.
- Gohil KJ, Patel JA, Gajjar AK. Pharmacological Review on Centella asiatica: A Potential Herbal Cure-all. Indian J Pharm Sci. 2010;72(5):546-556. doi:10.4103/0250-474X.78519
- Belcaro GV, Grimaldi R, Guidi G. Improvement of capillary permeability in patients with venous hypertension after treatment with TTFCA. Angiology. 1990;41(7):533-540. doi:10.1177/000331979004100705
- Cesarone MR, Incandela L, De Sanctis MT, et al. Evaluation of treatment of diabetic microangiopathy with total triterpenic fraction of Centella asiatica: a clinical prospective randomized trial with a microcirculatory model. Angiology. 2001;52 Suppl 2:S49-S54.
- Idris S, Mishra A, Khushtar M. Phytochemical, ethanomedicinal and pharmacological applications of escin from Aesculus hippocastanum L. towards future medicine. J Basic Clin Physiol Pharmacol. 2020;31(5):/j/jbcpp.2020.31.issue-5/jbcpp-2019-0115/ jbcpp-2019-0115.xml. Published 2020 Jul 10. doi:10.1515/ jbcpp-2019-0115
- Patel H, Skok C, DeMarco A. Peripheral Edema: Evaluation and Management in Primary Care. Am Fam Physician. 2022;106(5):557-564.
| Options | 90 CT |
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Brand
Ortho Molecular Products