Time Release Niacin
$29.10
Time Release Niacin is required by the body to promote the health and function of the digestive system, liver, skin and nerves.*
Niacin has long been used to lower triglycerides and to increase high-density lipoprotein (HDL) cholesterol. Time Release Niacin is most known for its broad cardiovascular benefits, but is also an important nutrient for bone health, blood sugar balance and cerebrovascular function. 5-9 Populations that consume adequate levels of niacin have been shown to have better outcomes for long-term health.10
Time Release Niacin, also known as vitamin B3, is a micronutrient with a 40-year history of efficacy in supporting healthy lipid levels, especially high-density lipoprotein cholesterol (HDL-C) levels. However, one side effect often makes supplementing niacin a less than pleasurable experience, limiting adherence. Some patients experience flushing when supplementing niacin. However, a properly manufactured, sustained-release niacin circumvents this side effect. By using a proprietary, natural wax-matrix coating technology, Time Release Niacin is released slowly over a six- to eight-hour period to reduce flushing.
HDL (high-density lipoprotein) cholesterol, sometimes called “good” cholesterol, absorbs cholesterol in the blood and carries it back to the liver. The liver then flushes it from the body. High levels of HDL cholesterol can lower your risk for heart disease and stroke.
Clinical Applications Niacin
- Promotes Healthy Blood Lipid Levels
- Supports Healthy High-Density Lipoprotein (HDL) Levels
- Maintains Healthy Low-Density Lipoprotein (LDL) Levels and Lipid Particle Size
- Maintains Healthy Triglyceride Levels
- Enhances Endothelial Function by Increasing Nitric Oxide Synthase
Symptoms of mild deficiency of niacin may include indigestion, fatigue, canker sores and depression. Niacin deficiency, if left unattended, can negatively affect brain function leading to apathy, fatigue, disorientation and memory loss.
Cardiovascular Health and Cholesterol Balance
Niacin has been used since the 1950s to maintain healthy balance of cholesterol levels. Since 1978, researchers have labeled niacin a “front-line” nutrient for cardiovascular support.
What is Niacin?
Niacin, also known as vitamin B3, is a micronutrient with a 40-year history of efficacy in supporting healthy lipid levels, especially high-density lipoprotein cholesterol (HDL-C) levels. However, one side effect often makes supplementing niacin a less than pleasurable experience, limiting adherence.
Some patients experience flushing when supplementing niacin. However, a properly- manufactured, sustainedrelease niacin circumvents this side effect. By using a proprietary, natural wax-matrix coating technology, Time Release Niacin is released slowly over a six- to eight-hour period to reduce flushing. This time period is considered the ideal window for releasing equal amounts of niacin into circulation as nicotinuric acid, the beneficial metabolite responsible for niacin’s lipid balancing benefits.1-2 In a double-blind placebo-controlled study, this specific form of Time Release Niacin had only a 5-7 % flush rate, making it well-tolerated and highly effective for supporting balanced cholesterol levels.
Does Not Contain
Gluten, corn, yeast, artificial colors and flavors.
Cautions
If you are pregnant or nursing, consult your physician before taking this product. This product is designed to release niacin over a six- to eight- hour period to minimize flushing (Avoiding hot beverages is recommended). A small percentage of people may still experience harmless flushing while taking this product.
Suggested Use:
1 tablet three times per day with a meal or as recommended by your health care professional.
References:
1. Keenan JM, Fontaine PL et al. Niacin revisited. A randomized, controlled trial of wax-matrix sustainedrelease niacin in hypercholesterolemia. Arch Intern Med. 1991 Jul;151(7):1424-32.information.
2. Keenan JM,Bae CY et al.Treatment of hypercholesterolemia: comparison of younger versus older patients using wax-matrix sustained-release niacin. J Am Geriatr Soc. 1992; 40(1):12-8.
3. Bissett DL, Oblong JE, Berge CA, et al. Niacinamide: A B vitamin that improves aging facial skin appearance. Dermatol Surg. 2005;31:860-865; discussion 865.
4. Benavente CA, Jacobson MK, Jacobson EL. NAD in skin: therapeutic approaches for niacin. Currr Pharm Des. 2009;15(1):29-38.
5. Elam M, Hunninghake DB, Davis KB, et al. Effects of niacin on lipid and lipoprotein levels and glycemic control in patients with diabetes and peripheral arterial disease: the ADMIT study: a randomized trial. Arterial Disease Multiple Intervention Trial. JAMA. 2000;284:1263-1270.
6. Canner PL, Furberg CD, Terrin ML, McGovern ME. Benefits of niacin by glycemic status in patients with healed myocardial infarction (from the Coronary Drug Project). Am J Cardiol. 2005; 95(2):254-7.
7. Guyton JR. Niacin in cardiovascular prevention: mechanisms, efficacy, and safety. Curr Opin Lipidol. 2007
Aug;18(4):415-20.
8. McKenney J. New perspectives on the use of niacin in the treatment of lipid disorders. Arch Intern Med. 2004 Apr 12;164(7):697-705.
9. Morgan JM,Carey CM,Lincoff A,Capuzzi DM. The effects of niacin on lipoprotein subclass distribution. Prev Cardiol. 2004; 7(4):182-7.
10. AIM-HIGH Investigators. The role of niacin in raising high-density lipoprotein cholesterol to reduce
cardiovascular events in patients with atherosclerotic cardiovascular disease and optimally treated low-density
lipoprotein cholesterol Rationale and study design. The Atherothrombosis Intervention in Metabolic syndrome with low HDL/high triglycerides: Impact on Global Health outcomes (AIMHIGH). Am Heart J. 2011 Mar;161(3):471-477.e2.
11. Kannel WB. Recent findings from the Framingham study—I. Med Times. 1978 Apr;106(4):23-27
12. Hulley SB. The US National Cholesterol Education Program. Adult treatment guidelines. Drugs. 1988;36 Suppl 3:100-04.
| Quantity | 90 tablets |
|---|
Brand
Ortho Molecular Products