Pregnenolone is a prohormone that is synthesized from cholesterol and can be converted to progesterone, DHEA and other hormones. Studies have shown that pregnenolone concentration is higher in the nervous system than in the blood stream, and it has been studied for its potential to promote sleep quality and memory, as well as its possible anti-aging properties.*

In functional medicine, pregnenolone is said to aid in the treatment of the following health problems:

• Alzheimer’s disease
• allergies
• Inflammation
• arthritis
• depression
• endometriosis
• fatigue
• fibrocystic breast condition
• menopausal symptoms
• multiple sclerosis
• Brain Fog
• Low Progesterone
• premenstrual syndrome
• psoriasis
• scleroderma

Uses For Pregnenolone

Memory Support: Animal studies have reported that pregnenolone may help to enhance memory by modulating N-methyl-D-aspartate (NMDA) and gamma aminobutyrate (GABA) receptor activity in the brain. One study suggested that pregnenolone helped promote post-training task learning and memory.*

Immune Health: One study indicated that the 7-hydroxy metabolites from pregnenolone may help promote healthy immune system
response.*

Mood Support: Pregnenolone has been reported to help promote feelings of emotional well-being. One study suggested that pregnenolone supported positive mood and feelings of motivation by mediating dopamine release.* Other studies show that it is helpful in depression and is well tolerated.

This product should not be taken by individuals with healthy levels of pregnenolone.

Adrenal Fatigue and Using Pregnenolone

Low levels of pregnenolone are often associated with Adrenal Fatigue Syndrome or Chronic Fatigue Syndrome. Adrenal Fatigue is a condition caused by chronic stress that is not well known among conventionally trained physicians. The symptoms of this condition are sometimes vague and difficult to recognize as a pattern that denotes a problem with adrenal output. However, these symptoms can become debilitating.

Most conventionally-trained physicians are not familiar with Adrenal fatigue and its symptoms. Conventionally trained physicians have no problem identifying excessively high levels of cortisol as being associated with Cushing’s Disease, and low levels of cortisol being associated with Addison’s Disease. However, these two extremes of adrenal function do not take into consideration any state in between. Tests used for these conditions only delineate the extremely high or low levels of cortisol. Those who have normal laboratory results but clinically symptomatic levels are ignored.

This wide range of unusual but not clinically problematic levels is called a subclinical state, and this is where those with Adrenal Fatigue Syndrome typically test.

Adrenal Fatigue is difficult to identify using standard medical blood tests. The tests used to check hormones related to the adrenals are designed to pick up extremely high or low levels, and will miss hormone levels that are outside the extremes. You may have hormone levels that are out of balance, or too low for optimal functioning, but these tests miss them.

The result is that patients are told they have normal hormone levels, or that their adrenals are functioning normally, when in fact they aren’t. Conventional medicine offers no help, or symptoms are addressed individually, with little or no relief resulting. Learn more about Adrenal Fatigue Testing here

Are There Any Precautions Or Potential Side Effects?

• NOT FOR USE BY INDIVIDUALS UNDER THE AGE OF 18.
• DO NOT USE IF PREGNANT OR NURSING.
• KEEP OUT OF REACH OF CHILDREN.

Consult a physician or licensed qualified health professional before using this product if you have, or have a family history of breast cancer, prostate cancer, prostate enlargement, heart disease, low “good” cholesterol (HDL), or if you are using any other dietary supplement, prescription drug, or over-the-counter drug.

Do not exceed the recommended serving. Exceeding the recommended serving may cause serious adverse health effects.

When using hormones it is always best to obtain baseline testing and retest within 3-4 months.

Potential Side Effects:

Possible side effects include acne, hair loss, hair growth on the face (in women), aggressiveness, irritability, and increased levels of
estrogen.

Discontinue use and call a physician or licensed qualified health professional immediately if you experience rapid heartbeat, dizziness, blurred vision, or other similar symptoms.

When taken at higher levels, irritability, over-stimulation and fatigue have been observed. Due to its effects on the GABA receptor in the central nervous system, supplementation with pregnenolone could cause problems in people with a history of
seizures.

Are There Any Potential Drug Interactions?

Pregnenolone may inhibit drugs used to increase GABA activity (e.g., Neurontin); these drugs are frequently used in the treatment of
epilepsy and depression.*

One Capsule Contains:

Other Ingredients: Hydroxypropyl methylcellulose (vegetable capsule), microcrystalline cellulose, rice flour, ascorbyl palmitate, silica.

Does Not Contain: Milk, eggs, fish, shellfish, tree nuts, peanuts, wheat, soy.

Size:
50c

Serving Size:
1 Capsule

Servings Per Container:
50

Directions:
Take one capsule per day or as directed by your healthcare practitioner.