BioSpora™

A Combination of Two powerful Spore-Forming Probiotics

BioSpora™ is a powerful, hypoallergenic blend of genetically certified Bacillus coagulans and B. subtilis species (Two powerful spore-forming probiotics ) formulated to provide unique probiotic support of healthy gastrointestinal and immune function.^† Spore-forming bacilli have often been referred to as soil-based microorganisms because of their ubiquitous presence in the earth.

When isolated from the human GI tract, spore-forming bacilli have long been thought to be transient bacteria. However, current research shows that Bacillus species are present in the GI tract in numbers higher than can be explained by ingestion alone.

Germination of Bacillus spores within the human small intestine and transient colonization is now thought to be part of the normal life cycle of human-associated Bacillus species providing specific stimuli for healthy GI and immune system development and function. Each capsule of BioSpora™ supplies a total of 2 billion CFUs of B. coagulans and B. subtilis spores positively identified through independent 16S ribosomal RNA gene sequencing.

The spores are resistant to extremes of heat, ultraviolet radiation, solvents, hydrogen peroxide, and enzymes. The spores withstand stomach acid and germinate in the small intestine within 6 hours of ingestion.

Ingested B. coagulans and B. subtilis reside in the human GI tract for up to 7 days following consumption.

What Are Spore Forming Probiotics 

Spore-forming probiotics are a type of probiotic that belongs to the Bacillus genus. Unlike traditional probiotics, which are often Lactobacillus and Bifidobacterium species, spore-forming probiotics are characterized by their ability to form spores. These spores are a dormant, resilient state that allows the bacteria to survive extreme environmental conditions, such as heat, acidity, and dehydration. Once they reach the gut, they can germinate, grow, and provide beneficial effects to the host.

BioSpora™ 

Provides short-term support for the GI and immune systems Spore-forming bacilli, oft en referred to as soil-based microorganisms, have long been thought to be transient bacteria in the human gastrointestinal (GI) tract. However, current research shows that Bacillus species are present in the GI tract in numbers higher than can be explained by ingestion alone.

Germination of Bacillus spores within the human small intestine and transient colonization is now thought to be part of the normal life cycle of human-associated Bacillus species, providing specific stimuli for healthy GI and immune system development and function.† BioSpora™ contains 2 beneficial Bacillus species suitable for short-term ingestion. • Bacillus coagulans produces lactic acid and short chain fatty acids nutritive to the colonic mucosa, promotes defenses against unfavorable bacteria, supports Th1 and Th2 immune responses, and promotes production of signaling compounds that support a healthy inflammatory response.†

B. subtilis produces nattokinase enzyme as well as bacteriocins that support healthy microbial balance in the gut.† Independently tested for genetic identity, potency, and purity Bacillus species are oft en used in over-thecounter probiotic products as they are hardy organisms that do not require refrigeration. However, commercial sources have long suffered from misclassification, allergen content, and even contamination with Bacillus spores with potential gastrointestinal toxicity. To overcome these safety concerns, each lot of Bacillus species used in BioSpora™ undergoes independent DNA testing using 16S ribosomal RNA sequencing to verify genetic identity. Independent tests on every batch also certify that BioSpora™ delivers its labeled potency and is free of milk allergen.

Resistant to extremes of heat, gastric acid, and enzymes Bacillus probiotic spores are resistant to heat and ambient humidity. No refrigeration is required. The spores are also resistant to ultraviolet radiation, solvents, hydrogen peroxide, and enzymes. The spores withstand stomach acid and germinate in the small intestine within 6 hours of ingestion. Ingested B. coagulans and B. subtilis reside in the human GI tract for up to 7 days following consumption.

9 Main Benefits of Spore Forming Probiotics and Why I recommend Them

Spore-based probiotics, also known as spore-forming probiotics or Bacillus probiotics, have gained increasing attention due to their unique properties and potential benefits. These types of probiotics come from bacterial spores that can survive the harsh conditions of the digestive system and offer various advantages over non-spore-forming probiotics. Below are the main benefits of spore-based probiotics:

1.Enhanced Survival and Stability

Resilience to Harsh Conditions: Spore-based probiotics can survive the acidic environment of the stomach and the bile salts in the small intestine. This ensures that a higher number of viable bacterial cells reach the intestines.

Long Shelf Life:  These probiotics are resistant to heat, desiccation, and other environmental stressors. This increases their stability and shelf life without the need for refrigeration.

2. Efficient Colonization

Germination in the Gut:  Once the spores reach the intestines, they can germinate and multiply, effectively colonizing the gut and exerting their beneficial effects.

Competitive Edge: Spore-based probiotics can outcompete pathogenic bacteria by producing antimicrobial compounds and occupying ecological niches in the gut.

Spore-based probiotics, also known as spore-forming probiotics or Bacillus probiotics, have gained increasing attention due to their unique properties and potential benefits. These types of probiotics come from bacterial spores that can survive the harsh conditions of the digestive system and offer various advantages over non-spore-forming probiotics. Below are the main benefits of spore-based probiotics:

3. Immune System Support 

Immunomodulation: These probiotics can help regulate the immune system, promoting a balanced immune response and reducing inflammation.

Enhanced Gut Barrier Function: By strengthening the gut lining, they can prevent the translocation of pathogens and toxins into the bloodstream.

 4. Gut Microbiome Balance

Diverse Microbial Support: Spore-based probiotics can stimulate the growth of beneficial bacteria in the gut, helping to maintain a healthy and diverse microbiome.

Inhibiting Pathogens: They produce substances that can inhibit the growth of harmful bacteria, yeasts, and other pathogens.

5. Digestive Health

Enzyme Production: Some spore-based probiotics produce digestive enzymes that aid in the breakdown and absorption of nutrients.

Alleviation of Digestive Disorders: They can help alleviate symptoms of Irritable Bowel Syndrome (IBS), inflammatory bowel disease (IBD), and other gastrointestinal disorders.

6. Detoxification

Binding and Neutralizing Toxins: Spore-based probiotics can bind to and neutralize various toxins, including those produced by pathogenic bacteria.

Supporting Liver Function: Some strains may aid in liver detoxification processes, improving overall detox efficiency.

7. Mental Health Benefits

Gut-Brain Axis: Emerging research suggests that these probiotics might influence the gut-brain axis, potentially alleviating symptoms of anxiety, depression, and other mental health conditions.

8. Minimal Risk of Overgrowth

Transitory Nature: Unlike some non-spore-forming probiotics, spore-based probiotics do not typically stay in the gut for extended periods, reducing the risk of overgrowth and imbalance.

Immunomodulation: These probiotics can help regulate the immune system, promoting a balanced immune response and reducing inflammation.

Enhanced Gut Barrier Function: By strengthening the gut lining, they can prevent the translocation of pathogens and toxins into the bloodstream.

9. Gut Microbiome Balance

Diverse Microbial Support: Spore-based probiotics can stimulate the growth of beneficial bacteria in the gut, helping to maintain a healthy and diverse microbiome.

Inhibiting Pathogens: They produce substances that can inhibit the growth of harmful bacteria, yeasts, and other pathogens.

Suggested use of Spore-Based Probiotics

1 capsule daily or as directed by a healthcare professional.

Caution:

If you are pregnant, nursing, have a medical condition, or taking prescription drugs, consult your healthcare professional before using this product. Keep out of reach of children. Product supply 60 or 120 vegetarian capsules per bottle. Storage Bacillus probiotic spores are resistant to heat and ambient humidity. No refrigeration is required.

BioSpora™ is indicated for short-term (less than 3 months) support of the gastrointestinal and immune systems.†

These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

It is certified free of casein, gluten, and soy. BioSpora™ does not require refrigeration